peptide-sequence-search The term hy peptide encompasses a fascinating class of molecules with profound implications in immunology, particularly concerning transplantation and sex-specific antigen recognition. These peptides, often derived from specific proteins, play a crucial role as H-Y antigens, acting as key players in immune responses.ClonaCell™-HYMedium E has proven effective for subcloning and stabilization of unstable hybridoma cell lines. Understanding the nature and function of hy peptide is vital for advancements in areas like organ transplantation and the study of immune tolerance.Smcy HY Peptide (738-746) - 金斯瑞生物科技有限公司
At its core, the H-Y antigen is defined as a male tissue specific antigen. This means it is predominantly found in male tissues and can elicit an immune response in females or in individuals with different genetic makeups. The discovery of H-Y antigens has been instrumental in understanding rejection mechanisms in transplantation, especially between individuals of different sexes. Research has identified various hy peptide sequences, each originating from specific genes and exhibiting distinct immunological properties.
Among the well-characterized hy peptide entities are those derived from the Smcy protein. The Smcy HY Peptide (738-746), for instance, is a specific sequence (amino acids 738-746) of the Smcy protein that is recognized as an H-Y antigen. This particular peptide is H2-Db restricted, indicating its presentation by a specific class of Major Histocompatibility Complex (MHC) molecules, a critical component of the immune system’s ability to distinguish self from non-self. Another significant entity is the Uty HY Peptide (246-254), mouse, which is derived from the mouse UTY (ubiquitously transcribed tetratricopeptide repeat gene on the Y chromosome). This male-specific transplantation antigen, H-Y, is a T-cell epitope, meaning it is recognized by T lymphocytes, a crucial type of immune cell.Dby HY Peptide (608-622) - 主营生物科研试剂&抗体|蛋白 Similarly, the Dby HY Peptide (608-622), mouse, is another identified hy peptide that is an HYAb epitope belonging to a well-conserved family of genes coding for RNA helicases.Human H-Y: A Male-Specific Histocompatibility Antigen ...
The study of hy peptide has also shed light on the intricate mechanisms by which immune tolerance can be induced.Dby HY Peptide (608-622), mouse - 1 mg - MoBiTec For example, research has demonstrated that the use of the intranasal route of administration of HY peptides can lead to the induction of transplantation tolerance to H-Y antigens in experimental models. This suggests potential therapeutic strategies for mitigating transplant rejection. The findings indicate that two peptides arise as a result of Y chromosome-regulated control of certain autosomal gene products, underscoring the complex genetic basis of these antigensSmcy HY Peptide(738-746). 该产品已下架。 MHC related. 产品编号, RP20273..
The identification and characterization of hy peptide are ongoing.Dby HY Peptide (608-622) - 主营生物科研试剂&抗体|蛋白 Scientists are continually discovering new peptides and refining our understanding of their roles满2000送100元京东卡 ; 英文名称,Dby HY Peptide (608-622), mouse ; 分子式, C60H97N25O ; 分子量, 1568.56 ; 纯度, ≥98% ; 外观(性状), Solid.. For instance, studies have explored novel HY Peptide Antigens Presented by HLA-B27, revealing further complexity in how these antigens are presented to the immune systemUty HY Peptide (246-254), mouse - 1 mg. The concept extends to various species, with researchers investigating H-Y in different contexts, such as the "HY peptides modulate transplantation responses to skin.UtyHY Peptide(246-254), derived from the ubiquitously transcribed tetratricopeptide repeat gene on the Y chromosome (UTY) protein as an H-Y epitope, .....作者:W Wang·1995·被引用次数:429—As with other minor H antigens, the recognition ofH-Yby T lymphocytes is. MHC-restricted (3, 9), and someH-Yan- tigens arepeptidesderived from cellular." studiesThis T-cell epitope WMHHNMDLI is amale-specific transplantation antigen, H-Y, derived from mouse UTY (ubiquitously transcribed tetratricopeptide repeat gene on ....
For researchers and laboratories, obtaining specific hy peptide is crucial for experimental work. Companies offer various hy peptide for research purposes, such as the Uty HY Peptide (246-254) Mouse CRB1000446, which can be purchased for pharmaceutical testing and as high-quality reference standards. It's important to note that many of these peptides, like the Smcy HY Peptide 738-746, are intended for research use only and are not for human consumption. The availability of specific sequences like Dby HY Peptide (608-622) and Uty HY Peptide (246-254), mouse - 1 mg allows for detailed investigations into their structure-function relationships and immunological impact.作者:WA Simmons·1997·被引用次数:37—We have identifiedtwo peptides corresponding to the male-specific HY minor histocompatibility Agspresented by HLA-B27 in transgenic ...
Beyond their direct role in transplantation, the study of hy peptide touches upon broader themes in molecular biology and materials science. For example, the principles of amino-acid- and peptide-directed synthesis of chiral gold nanoparticles highlight how the precise arrangement of amino acids, the building blocks of peptides, can influence the properties of materials at the nanoscale.Uty HY Peptide (246-254), mouse, T-cell epitope WMHHNMDLI is amale-specific transplantation antigen, H-Y, derived from mouse UTY. This demonstrates the versatile applications of understanding peptide structures and interactions.
In summary, the field of hy peptide research is a dynamic and evolving area. From the foundational understanding of H-Y as a male tissue specific antigen to the intricate details of specific peptides like Smcy HY Peptide (738-746) and Uty HY Peptide (246-254), mouse, these molecules are central to unraveling complex immunological processes. The ongoing exploration of hy peptide promises to yield significant advancements in transplantation medicine, immune tolerance, and our fundamental knowledge of biological recognition.
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